Wisepowder Oleoylethanolamide- A Natural Satiety Provider In Human Body

A Natural Satiety Provider In Human Body


OEA(Oleoylethanolamide) is a molecule that is produced in the body and found in the intestine. It is a natural satiety booster after eating in our body. As we know, Obesity is one the most common disease that nearly everyone suffers from and this obesity is caused due to the extra fat produced in our body and this OEA is proven to burn the excess fat of the body. It is an alpha lipid molecule and is a Receptor molecule known as PPAR- Alpha i.e. Peroxisome Proliferator Activated Receptor Alpha. It is endogenous in nature. OEA belongs to Amide group known as ethanolamine and has a IUPAC name of (Z)-N-(2-Hydroxyethyl)octadec-9-enamide.It is produced by the small intestine where the final most nutrition absorption takes place. It is a lipid that regulated feeding and weight in all vertebrates starting from mice to other larger vertebrates. It regulated the PPAR-Alpha activity to stimulate lipolysis by working independent of the Cannabinoid pathway unlike anandamide. OEA is a monosaturatedanalogue of the endocannabinoid anandamide. OEA is an active molecule of Riduzone.

Composition and nature of Oleoylethanolamide (OEA)

Wisepowder oleoylethanolamide is a derivative of oleic acid. Oleic acid is a monosaturated fatty acid that regulates body composition. OEA(C20H39NO2) is a composition of twenty molecules of carbon carbon atom, thirty-nine molecules of hydrogen atom, one molecule of nitrogen atom and two molecules of oxygen atom. Oleoylethanolamide is a white solid having a molecular mass of 325.547gm/mol. It is soluble in ethanol. Its molecule is shorter in size.

Benefits of Oleoylethanolamide

As it is a molecule produced in our body it has many benefits as well. A research has been made to find out the benefits of Oleoylethanolamide on human body. For this 60 obese people’s were given two 125 mg OEA capsule daily for 60 days and the following results has been recorded.

  • It is a fat reducing agent-It is a good supplement used to reduce body weight. Intake if OEA reduces your food intake as a result you have a feeling of fullness. Thus it is proven to lose weight in humans. It has been proved to reduce 2 pounds
  • It curbs appetite– OEA is a dietary supplement that reduces your cravings for food by activating the PPAR-Alpha receptors. OEA directly send a signal to the brain thereby reducing your appetite. It is a supplement that reduces 200-250 mg of food intake daily.
  • OEA inhibits gastric emptying and intestine motility– Taking OEA reduces the cravings for sweets and other junk foods. As a result of which all gastritis problems doesn’t occur along with a healthy intestine functioning. Oleic acid is a fatty acid that breaks down monosaturated fatty acid in human body.
  • If is responsible for feeling of satiety after food– It regulates the average food intake in every body. So, there is a feeling of fullness ad satiety after every meal.
  • OEA acts as a receptor molecule– OEA acts as a receptor molecule called PPAR-Alpha. Once this molecule is released in the small intestine of any vertebrate, it reduces the food intake in them. There is a research on rats shows that either oral or injecting OEA to their body substantially reduces the food intake like wisepowder Glutathione benefits .


As OEA is referred to be a good supplement. As we know every dietary supplement has it’s side effects. But OEA’s side effect has not yet found as it is a molecule found in the body. It is assumed that it will not have any side effects. But it is better to consult a doctor before taking OEA capsules. If you want to consume OEA then you can eat foods that contain this molecule like oatmeal.

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